Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL824707

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The binding affinity was measured on trypsin obtained from Human purified enzymes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Serine protease 1 (CHEMBL209)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 1.
Quan ML, Liauw AY, Ellis CD, Pruitt JR, Carini DJ, Bostrom LL, Huang PP, Harrison K, Knabb RM, Thoolen MJ, Wong PC, Wexler RR.
J Med Chem (1999) 42 : 2752 -2759
PubMed 10425086 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.26 7.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1202108 1 7.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1202108 Ki = 55.0 nM 7.26