Assay Detail
Functional
CHEMBL824873
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of Plasmodium falciparum F32
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Toward a novel metal-based chemotherapy against tropical diseases. 7. Synthesis and in vitro antimalarial activity of new gold-chloroquine complexes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.86 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL58510 | CHLOROQUINE PHOSPHATE | 4.0 | 1 | 8.00 |
| CHEMBL184449 | Gold-Chloroquine Complex | — | 1 | 8.00 |
| CHEMBL363104 | Gold-Chloroquine Complex | — | 1 | 7.89 |
| CHEMBL186506 | Gold-Chloroquine Complex | — | 1 | 7.89 |
| CHEMBL189068 | Gold-Chloroquine Complex | — | 1 | 7.77 |
| CHEMBL184465 | Gold-Chloroquine Complex | — | 1 | 7.75 |
| CHEMBL187626 | Gold-Chloroquine Complex | — | 1 | 7.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL58510 | CHLOROQUINE PHOSPHATE | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL184449 | Gold-Chloroquine Complex | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL363104 | Gold-Chloroquine Complex | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL186506 | Gold-Chloroquine Complex | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL189068 | Gold-Chloroquine Complex | IC50 | = | 17.0 | nM | 7.77 |
| CHEMBL184465 | Gold-Chloroquine Complex | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL187626 | Gold-Chloroquine Complex | IC50 | = | 18.0 | nM | 7.75 |