Assay Detail
Functional
CHEMBL825143
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Inhibitory concentration againstHuman Caki-1 Renal CellCarcinoma Cell Lines (CD70+) at 96th hour; n=1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CAKI-1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and in vitro evaluation of dipeptide-based antibody minor groove binder conjugates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.26 | 9.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL179092 | — | — | 1 | 9.35 |
| CHEMBL117142 | — | — | 1 | 9.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL179092 | — | IC50 | = | 0.45 | nM | 9.35 |
| CHEMBL117142 | — | IC50 | = | 0.68 | nM | 9.17 |