Assay Detail
Binding
CHEMBL826969
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Inhibitory activity against alpha-Glucosidase from rice
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | rice |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Alpha-1-C-alkyl-1-deoxynojirimycin derivatives as potent and selective inhibitors of intestinal isomaltase: remarkable effect of the alkyl chain length on glycosidase inhibitory profile.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.82 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL186068 | — | — | 1 | 7.10 |
| CHEMBL187158 | — | — | 1 | 7.10 |
| CHEMBL186291 | — | — | 1 | 6.23 |
| CHEMBL186150 | — | — | 1 | 6.16 |
| CHEMBL364554 | — | — | 1 | 6.10 |
| CHEMBL184028 | — | — | 1 | 5.82 |
| CHEMBL362754 | — | — | 1 | 5.70 |
| CHEMBL3351101 | — | — | 1 | 4.96 |
| CHEMBL187208 | — | — | 1 | 4.82 |
| CHEMBL3349976 | — | — | 1 | 4.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL186068 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL187158 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL186291 | — | IC50 | = | 590.0 | nM | 6.23 |
| CHEMBL186150 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL364554 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL184028 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL362754 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL3351101 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL187208 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL3349976 | — | IC50 | = | 61000.0 | nM | 4.21 |