Assay Detail
Binding
CHEMBL827183
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]PGD-2 from human Prostanoid DP receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Discovery of diphenylcarbamate derivatives as highly potent and selective IP receptor agonists: orally active prostacyclin mimetics. Part 3.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.64 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL196779 | — | — | 1 | 5.64 |
| CHEMBL132589 | — | — | 1 | - |
| CHEMBL190497 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL196779 | — | Ki | = | 2300.0 | nM | 5.64 |
| CHEMBL132589 | — | Ki | > | 1000.0 | nM | - |
| CHEMBL190497 | — | Ki | > | 1000.0 | nM | - |