Assay Detail
Binding
CHEMBL827841
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Inhibitory activity against alpha-Glucosidase from Yeast
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Alpha-1-C-alkyl-1-deoxynojirimycin derivatives as potent and selective inhibitors of intestinal isomaltase: remarkable effect of the alkyl chain length on glycosidase inhibitory profile.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.38 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL186291 | — | — | 1 | 4.60 |
| CHEMBL364554 | — | — | 1 | 4.28 |
| CHEMBL184028 | — | — | 1 | 4.25 |
| CHEMBL3351101 | — | — | 1 | - |
| CHEMBL187208 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL186291 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL364554 | — | IC50 | = | 52000.0 | nM | 4.28 |
| CHEMBL184028 | — | IC50 | = | 56000.0 | nM | 4.25 |
| CHEMBL3351101 | — | IC50 | = | 465000.0 | nM | - |
| CHEMBL187208 | — | IC50 | = | 630000.0 | nM | - |