Assay Detail
Binding
CHEMBL827895
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Fibroblast growth factor receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Fibroblast growth factor receptor (CHEMBL2095217) ↗| Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
Publication
Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.10 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL190281 | — | — | 1 | 7.10 |
| CHEMBL192308 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL190281 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL192308 | — | IC50 | > | 5000.0 | nM | - |