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Assay Detail

CHEMBL828006

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration of compound on platelet aggregation
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Effects of 5'-phosphate derivatives of 2-hexynyl adenosine and 2-phenylethynyl adenosine on responses of human platelets mediated by P2Y receptors.
Cristalli G, Podda GM, Costanzi S, Lambertucci C, Lecchi A, Vittori S, Volpini R, Zighetti ML, Cattaneo M.
J Med Chem (2005) 48 : 2763 -2766
PubMed 15828813 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.15 4.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL609343 1 4.22
CHEMBL1199140 1 4.07
CHEMBL610853 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL609343 IC50 = 60000.0 nM 4.22
CHEMBL1199140 IC50 = 85000.0 nM 4.07
CHEMBL610853 IC50 = 130000.0 nM -