Assay Detail
Binding
CHEMBL828013
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Inhibition of [3H]YM-09151-2 binding to human Dopamine D4 receptor expressed in CHO cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.13 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL25236 | BP-897 | — | 1 | 6.52 |
| CHEMBL301242 | — | — | 1 | 5.73 |
| CHEMBL300780 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL25236 | BP-897 | Ki | = | 300.0 | nM | 6.52 |
| CHEMBL301242 | — | Ki | = | 1850.0 | nM | 5.73 |
| CHEMBL300780 | — | Ki | > | 5000.0 | nM | - |