Assay Detail
Binding
CHEMBL828056
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Matrix metalloprotease-2 in MMPi assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
A new development of matrix metalloproteinase inhibitors: twin hydroxamic acids as potent inhibitors of MMPs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.04 | 9.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL362651 | — | — | 1 | 9.39 |
| CHEMBL262397 | — | — | 1 | 8.01 |
| CHEMBL196647 | — | — | 1 | 6.71 |
| CHEMBL382781 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL362651 | — | IC50 | = | 0.41 | nM | 9.39 |
| CHEMBL262397 | — | IC50 | = | 9.8 | nM | 8.01 |
| CHEMBL196647 | — | IC50 | = | 197.0 | nM | 6.71 |
| CHEMBL382781 | — | IC50 | > | 10000.0 | nM | - |