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Assay Detail

CHEMBL828061

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of 5-hydroxytryptamine 1D receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Indolebutylamines as selective 5-HT(1A) agonists.
Heinrich T, Böttcher H, Bartoszyk GD, Greiner HE, Seyfried CA, Van Amsterdam C.
J Med Chem (2004) 47 : 4677 -4683
PubMed 15341483 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.28 6.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL363537 1 6.40
CHEMBL360419 1 6.16
CHEMBL187196 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL363537 IC50 = 400.0 nM 6.40
CHEMBL360419 IC50 = 700.0 nM 6.16
CHEMBL187196 IC50 > 1000.0 nM -