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Assay Detail

CHEMBL828250

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Binding
Binding affinity against rabbit muscle triose-phosphate isomerase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryctolagus cuniculus
Tissue Muscle tissue
Confidence 9 — Direct single protein target
Curated By Expert

Target

Triosephosphate isomerase (CHEMBL3930)
Type SINGLE PROTEIN
Organism Oryctolagus cuniculus

Publication

New inhibitors of rabbit muscle triose-phosphate isomerase.
Fonvielle M, Mariano S, Therisod M.
Bioorg Med Chem Lett (2005) 15 : 2906 -2909
PubMed 15911278 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 5.44 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL371668 PHOSPHOGLYCOLOHYDROXAMATE 1 5.52
CHEMBL195976 1 5.35
CHEMBL195520 PHOSPHORIC ACID MONOHYDRAZINOCARBONYLMETHYL ESTER 1 -
CHEMBL196442 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL371668 PHOSPHOGLYCOLOHYDROXAMATE Ki = 3000.0 nM 5.52
CHEMBL195976 Ki = 4500.0 nM 5.35
CHEMBL195520 PHOSPHORIC ACID MONOHYDRAZINOCARBONYLMETHYL ESTER Ki = 111000.0 nM -
CHEMBL196442 Ki = 159000.0 nM -