Assay Detail
Binding
CHEMBL828258
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity against human cloned Dopamine receptor D3 stably expressed in CHO-K1 cells using [3H]spiperone
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO-K1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
N1-arylsulfonyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives are potent and selective 5-HT6 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.17 | 6.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL362487 | — | — | 1 | 6.20 |
| CHEMBL180606 | — | — | 1 | 6.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL362487 | — | Ki | = | 627.0 | nM | 6.20 |
| CHEMBL180606 | — | Ki | = | 741.0 | nM | 6.13 |