Assay Detail
Binding
CHEMBL828295
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human Phosphodiesterase 4D3 expressed in baculovirus infected Sf9 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
3',5'-cyclic-AMP phosphodiesterase 4D (CHEMBL288) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.01 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL185296 | — | — | 1 | 6.16 |
| CHEMBL182703 | — | — | 1 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL185296 | — | IC50 | = | 690.0 | nM | 6.16 |
| CHEMBL182703 | — | IC50 | = | 1420.0 | nM | 5.85 |