Assay Detail
Binding
CHEMBL828398
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human mineralocorticoid receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Antidiabetic activity of passive nonsteroidal glucocorticoid receptor modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.90 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL185265 | — | — | 1 | 6.92 |
| CHEMBL190225 | — | — | 1 | 6.16 |
| CHEMBL190109 | — | — | 1 | 6.00 |
| CHEMBL1276308 | MIFEPRISTONE | 4.0 | 1 | 5.22 |
| CHEMBL363151 | — | — | 1 | 5.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL185265 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL190225 | — | IC50 | = | 690.0 | nM | 6.16 |
| CHEMBL190109 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL1276308 | MIFEPRISTONE | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL363151 | — | IC50 | = | 6300.0 | nM | 5.20 |