Assay Detail
Binding
CHEMBL828818
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Binding affinity for cannabinoid receptor 1
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 7.35 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL559612 | CP-55940 | — | 1 | 8.85 |
| CHEMBL188 | WIN-552122 | — | 1 | 8.00 |
| CHEMBL146346 | — | — | 1 | 7.68 |
| CHEMBL321585 | — | — | 1 | 7.47 |
| CHEMBL465 | DRONABINOL | 4.0 | 1 | 7.43 |
| CHEMBL121229 | — | — | 1 | 7.28 |
| CHEMBL15848 | ANANDAMIDE | — | 1 | 7.14 |
| CHEMBL138921 | ARACHIDONOYL DOPAMINE | — | 1 | 6.60 |
| CHEMBL187349 | — | — | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL559612 | CP-55940 | Ki | = | 1.4 | nM | 8.85 |
| CHEMBL188 | WIN-552122 | Ki | = | 9.9 | nM | 8.00 |
| CHEMBL146346 | — | Ki | = | 21.0 | nM | 7.68 |
| CHEMBL321585 | — | Ki | = | 34.0 | nM | 7.47 |
| CHEMBL465 | DRONABINOL | Ki | = | 37.0 | nM | 7.43 |
| CHEMBL121229 | — | Ki | = | 53.0 | nM | 7.28 |
| CHEMBL15848 | ANANDAMIDE | Ki | = | 72.0 | nM | 7.14 |
| CHEMBL138921 | ARACHIDONOYL DOPAMINE | Ki | = | 250.0 | nM | 6.60 |
| CHEMBL187349 | — | Ki | = | 1900.0 | nM | 5.72 |