Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL828827

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of [3H]PGE-2 binding to Prostanoid EP2 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Prostaglandin E2 receptor EP2 subtype (CHEMBL1881)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Metabolism investigation leading to novel drug design: orally active prostacyclin mimetics. Part 4.
Hattori K, Takamura F, Tanaka A, Takasugi H, Taniguchi K, Nishio M, Koyama S, Seki J, Sakane K.
Bioorg Med Chem Lett (2005) 15 : 3284 -3287
PubMed 15935659 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.85 5.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2373410 1 5.85
CHEMBL132589 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2373410 Ki = 1400.0 nM 5.85
CHEMBL132589 Ki > 1000.0 nM -