Assay Detail
Binding
CHEMBL828883
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards human D2 long receptor using [3H]spiperone expressed in CHO cells
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.57 | 7.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL184993 | — | — | 1 | 7.32 |
| CHEMBL182379 | — | — | 1 | 7.23 |
| CHEMBL182652 | — | — | 1 | 7.12 |
| CHEMBL362101 | — | — | 1 | 7.05 |
| CHEMBL183871 | — | — | 1 | 6.35 |
| CHEMBL184383 | — | — | 1 | 5.50 |
| CHEMBL59725 | — | — | 1 | 5.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL184993 | — | Ki | = | 48.0 | nM | 7.32 |
| CHEMBL182379 | — | Ki | = | 59.0 | nM | 7.23 |
| CHEMBL182652 | — | Ki | = | 75.0 | nM | 7.12 |
| CHEMBL362101 | — | Ki | = | 89.0 | nM | 7.05 |
| CHEMBL183871 | — | Ki | = | 450.0 | nM | 6.35 |
| CHEMBL184383 | — | Ki | = | 3200.0 | nM | 5.50 |
| CHEMBL59725 | — | Ki | = | 3600.0 | nM | 5.44 |