Assay Detail
Binding
CHEMBL828923
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Inhibition constant against synaptosomal Mu opioid receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
From the potent and selective mu opioid receptor agonist H-Dmt-d-Arg-Phe-Lys-NH(2) to the potent delta antagonist H-Dmt-Tic-Phe-Lys(Z)-OH.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 9.63 | 10.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3143757 | — | — | 1 | 10.72 |
| CHEMBL2181202 | — | — | 1 | 9.85 |
| CHEMBL371856 | — | — | 1 | 9.82 |
| CHEMBL3143756 | — | — | 1 | 8.94 |
| CHEMBL370701 | — | — | 1 | 8.84 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3143757 | — | Ki | = | 0.019 | nM | 10.72 |
| CHEMBL2181202 | — | Ki | = | 0.143 | nM | 9.85 |
| CHEMBL371856 | — | Ki | = | 0.15 | nM | 9.82 |
| CHEMBL3143756 | — | Ki | = | 1.14 | nM | 8.94 |
| CHEMBL370701 | — | Ki | = | 1.45 | nM | 8.84 |