Assay Detail
Binding
CHEMBL828976
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]-BTX binding to Nicotinic acetylcholine receptor alpha-7 of rat hippocampal membranes
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Neuronal acetylcholine receptor subunit alpha-7 (CHEMBL4980) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Corrigendum to Epibatidine structureactivity relationships
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.97 | 8.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL186302 | — | — | 1 | 8.41 |
| CHEMBL186070 | — | — | 1 | 8.20 |
| CHEMBL185667 | — | — | 1 | 5.80 |
| CHEMBL363973 | — | — | 1 | 5.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL186302 | — | Ki | = | 3.9 | nM | 8.41 |
| CHEMBL186070 | — | Ki | = | 6.3 | nM | 8.20 |
| CHEMBL185667 | — | Ki | = | 1600.0 | nM | 5.80 |
| CHEMBL363973 | — | Ki | = | 3300.0 | nM | 5.48 |