Assay Detail
Binding
CHEMBL829079
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Inhibition of protein-bound lysine binding to Lysyl oxidase of porcine aorta
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Tissue | Aorta |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Alkylamino derivatives of 4-aminomethylpyridine as inhibitors of copper-containing amine oxidases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.00 | 4.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL536719 | — | — | 1 | 4.00 |
| CHEMBL536484 | — | — | 1 | 4.00 |
| CHEMBL537401 | — | — | 1 | - |
| CHEMBL536951 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL536719 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL536484 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL537401 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL536951 | — | IC50 | > | 1000000.0 | nM | - |