Assay Detail

CHEMBL829093

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibitory concentration against Nicotinic acetylcholine receptor alpha-6-alpha-3-beta-2; Range is 0.3-1.5 nM

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations.

Jensen AA, Frølund B, Liljefors T, Krogsgaard-Larsen P.
J Med Chem (2005) 48 : 4705 -4745
PubMed 16033252 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.82	8.82

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL411146	—	—	1	8.82

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL411146	—	IC50	=	1.5	nM	8.82