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Assay Detail

CHEMBL829240

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Cyclin-dependent kinase 2
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Cyclin-dependent kinase 2 (CHEMBL301)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Conformation mining: an algorithm for finding biologically relevant conformations.
Putta S, Landrum GA, Penzotti JE.
J Med Chem (2005) 48 : 3313 -3318
PubMed 15857136 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 7.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1276446 1 8.00
CHEMBL102926 1 8.00
CHEMBL101311 1 6.00
CHEMBL191845 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1276446 IC50 = 10.0 nM 8.00
CHEMBL102926 IC50 = 10.0 nM 8.00
CHEMBL101311 IC50 = 1000.0 nM 6.00
CHEMBL191845 IC50 = 1000.0 nM 6.00