Assay Detail
Binding
CHEMBL829331
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Inhibitory concentration against Beta Glucosidase from Almonds
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Prunus dulcis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Total asymmetric synthesis of (-)-conduramine B-1 and of its enantiomer. N-Benzyl derivatives of conduramine B-1 are beta-glucosidase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.38 | 4.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL365530 | — | — | 1 | 4.50 |
| CHEMBL189574 | — | — | 1 | 4.50 |
| CHEMBL191507 | — | — | 1 | 4.50 |
| CHEMBL189578 | — | — | 1 | 4.50 |
| CHEMBL191685 | — | — | 1 | 4.46 |
| CHEMBL191983 | — | — | 1 | 4.28 |
| CHEMBL370255 | — | — | 1 | 4.18 |
| CHEMBL190256 | — | — | 1 | 4.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL365530 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL189574 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL191507 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL189578 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL191685 | — | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL191983 | — | IC50 | = | 52000.0 | nM | 4.28 |
| CHEMBL370255 | — | IC50 | = | 66000.0 | nM | 4.18 |
| CHEMBL190256 | — | IC50 | = | 72000.0 | nM | 4.14 |