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Assay Detail

CHEMBL829476

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory concentration against beta-glucosidase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Cytosolic beta-glucosidase (CHEMBL3865)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Biological properties of D- and L-1-deoxyazasugars.
Kato A, Kato N, Kano E, Adachi I, Ikeda K, Yu L, Okamoto T, Banba Y, Ouchi H, Takahata H, Asano N.
J Med Chem (2005) 48 : 2036 -2044
PubMed 15771446 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.16 4.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL368121 1 4.22
CHEMBL307429 DUVOGLUSTAT 2.0 1 4.10
CHEMBL369297 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL368121 IC50 = 60000.0 nM 4.22
CHEMBL307429 DUVOGLUSTAT IC50 = 80000.0 nM 4.10
CHEMBL369297 IC50 = 980000.0 nM -