Assay Detail
Functional
CHEMBL829577
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against dipeptidyl peptidase IV in Caco-2 cell assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Caco-2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and DP-IV inhibition of cyano-pyrazoline derivatives as potent anti-diabetic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.99 | 6.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL184651 | — | — | 1 | 6.39 |
| CHEMBL185222 | — | — | 1 | 5.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL184651 | — | IC50 | = | 410.0 | nM | 6.39 |
| CHEMBL185222 | — | IC50 | = | 2620.0 | nM | 5.58 |