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Assay Detail

CHEMBL829625

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of [3H]YM-09151-2 binding to primate Dopamine D2L receptor expressed in CHO cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type CHO
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents.
Newman AH, Grundt P, Nader MA.
J Med Chem (2005) 48 : 3663 -3679
PubMed 15916415 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 6.86 7.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL301242 1 7.05
CHEMBL300780 1 6.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL301242 Ki = 89.0 nM 7.05
CHEMBL300780 Ki = 217.0 nM 6.66