Assay Detail
Binding
CHEMBL829634
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Binding affinity towards 5-HT2 receptor from porcine cortical membranes using [3H]ketanserin
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.32 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL362101 | — | — | 1 | 6.68 |
| CHEMBL182379 | — | — | 1 | 6.64 |
| CHEMBL184993 | — | — | 1 | 6.60 |
| CHEMBL183871 | — | — | 1 | 6.54 |
| CHEMBL182652 | — | — | 1 | 6.16 |
| CHEMBL184383 | — | — | 1 | 6.10 |
| CHEMBL59725 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL362101 | — | Ki | = | 210.0 | nM | 6.68 |
| CHEMBL182379 | — | Ki | = | 230.0 | nM | 6.64 |
| CHEMBL184993 | — | Ki | = | 250.0 | nM | 6.60 |
| CHEMBL183871 | — | Ki | = | 290.0 | nM | 6.54 |
| CHEMBL182652 | — | Ki | = | 690.0 | nM | 6.16 |
| CHEMBL184383 | — | Ki | = | 790.0 | nM | 6.10 |
| CHEMBL59725 | — | Ki | = | 3000.0 | nM | 5.52 |