Assay Detail
Binding
CHEMBL829665
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Inhibition of rat Dopamine D3 receptor expressed in HEK 293 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.93 | 9.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL69451 | — | — | 1 | 9.22 |
| CHEMBL302374 | — | — | 1 | 8.85 |
| CHEMBL262724 | — | — | 1 | 8.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL69451 | — | Ki | = | 0.6 | nM | 9.22 |
| CHEMBL302374 | — | Ki | = | 1.4 | nM | 8.85 |
| CHEMBL262724 | — | Ki | = | 1.9 | nM | 8.72 |