Assay Detail
Binding
CHEMBL829683
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]epibatidine binding to rat Nicotinic acetylcholine receptor alpha4-beta2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
Neuronal acetylcholine receptor; alpha4/beta2 (CHEMBL1907596) ↗| Type | PROTEIN COMPLEX |
| Organism | Rattus norvegicus |
Publication
6-(2-Phenylethyl)nicotine: a novel nicotinic cholinergic receptor ligand.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.08 | 7.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3 | NICOTINE | 4.0 | 1 | 7.46 |
| CHEMBL190295 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3 | NICOTINE | Ki | = | 35.0 | nM | 7.46 |
| CHEMBL190295 | — | Ki | = | 200.0 | nM | 6.70 |