Assay Detail
Binding
CHEMBL830021
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Inhibition of beta-phenylethylamine binding to Hansenula polymorpha amine oxidase
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Ogataea angusta |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Alkylamino derivatives of 4-aminomethylpyridine as inhibitors of copper-containing amine oxidases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 4.03 | 4.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL537624 | — | — | 1 | 4.06 |
| CHEMBL534467 | — | — | 1 | 4.00 |
| CHEMBL537175 | — | — | 1 | - |
| CHEMBL537174 | — | — | 1 | - |
| CHEMBL537402 | — | — | 1 | - |
| CHEMBL557160 | — | — | 1 | - |
| CHEMBL537628 | — | — | 1 | - |
| CHEMBL541126 | — | — | 1 | - |
| CHEMBL559376 | — | — | 1 | - |
| CHEMBL536949 | — | — | 1 | - |
| CHEMBL537401 | — | — | 1 | - |
| CHEMBL537623 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL537624 | — | IC50 | = | 87000.0 | nM | 4.06 |
| CHEMBL534467 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL537175 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL537174 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL537402 | — | IC50 | = | 700000.0 | nM | - |
| CHEMBL557160 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL537628 | — | IC50 | > | 300000.0 | nM | - |
| CHEMBL541126 | — | IC50 | = | 540000.0 | nM | - |
| CHEMBL559376 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL536949 | — | IC50 | = | 750000.0 | nM | - |
| CHEMBL537401 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL537623 | — | IC50 | = | 350000.0 | nM | - |