Assay Detail
Binding
CHEMBL830025
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
Neuronal acetylcholine receptor; alpha3/beta2 (CHEMBL2109234) ↗| Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
Publication
Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.70 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL606669 | — | — | 1 | 7.89 |
| CHEMBL111659 | ALTINICLINE | 2.0 | 1 | 5.50 |
| CHEMBL187927 | DIANICLINE | 3.0 | 1 | - |
| CHEMBL189861 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL606669 | — | EC50 | = | 13.0 | nM | 7.89 |
| CHEMBL111659 | ALTINICLINE | EC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL187927 | DIANICLINE | EC50 | > | 100000.0 | nM | - |
| CHEMBL189861 | — | EC50 | > | 100000.0 | nM | - |