Assay Detail
Binding
CHEMBL830159
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration of the compound was determined against neuraminidase B (B/Memphis/3/89) of Influenza virus
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Influenza B virus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Neuraminidase (CHEMBL3377) ↗| Type | SINGLE PROTEIN |
| Organism | Influenza B virus (strain B/Lee/1940) |
Publication
Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.42 | 7.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL369125 | — | — | 1 | 7.25 |
| CHEMBL183817 | — | — | 1 | 6.02 |
| CHEMBL182628 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL369125 | — | IC50 | = | 56.0 | nM | 7.25 |
| CHEMBL183817 | — | IC50 | = | 960.0 | nM | 6.02 |
| CHEMBL182628 | — | IC50 | = | 1000.0 | nM | 6.00 |