Assay Detail
Binding
CHEMBL830251
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Inhibition of [3H]spiperone binding to human Dopamine D3 receptor expressed in CHO cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.06 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL59725 | — | — | 1 | 9.30 |
| CHEMBL139926 | — | — | 1 | 8.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL59725 | — | Ki | = | 0.5 | nM | 9.30 |
| CHEMBL139926 | — | Ki | = | 1.5 | nM | 8.82 |