Assay Detail
Binding
CHEMBL830300
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against human Trypsin
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Synthesis and structure-activity relationships of novel selective factor Xa inhibitors with a tetrahydroisoquinoline ring.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.54 | 6.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL539053 | DX-9065A HYDROCHLORIDE HYDRATE | — | 1 | 6.21 |
| CHEMBL195428 | — | — | 1 | 4.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL539053 | DX-9065A HYDROCHLORIDE HYDRATE | Ki | = | 620.0 | nM | 6.21 |
| CHEMBL195428 | — | Ki | = | 13600.0 | nM | 4.87 |