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Assay Detail

CHEMBL830343

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against class II fructose-bisphosphate aldolase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

New inhibitors of rabbit muscle triose-phosphate isomerase.
Fonvielle M, Mariano S, Therisod M.
Bioorg Med Chem Lett (2005) 15 : 2906 -2909
PubMed 15911278 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 6.70 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL371668 PHOSPHOGLYCOLOHYDROXAMATE 1 8.00
CHEMBL195520 PHOSPHORIC ACID MONOHYDRAZINOCARBONYLMETHYL ESTER 1 6.47
CHEMBL195976 1 5.64
CHEMBL196442 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL371668 PHOSPHOGLYCOLOHYDROXAMATE Ki = 10.0 nM 8.00
CHEMBL195520 PHOSPHORIC ACID MONOHYDRAZINOCARBONYLMETHYL ESTER Ki = 340.0 nM 6.47
CHEMBL195976 Ki = 2300.0 nM 5.64
CHEMBL196442 Ki = 145000.0 nM -