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Assay Detail

CHEMBL830850

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Binding
Inhibitory concentration against human histone deacetylase (HDAC) from HeLa cells with substrate 5a
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HeLa
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Histone deacetylase (CHEMBL2093865)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Subtype selective substrates for histone deacetylases.
Heltweg B, Dequiedt F, Marshall BL, Brauch C, Yoshida M, Nishino N, Verdin E, Jung M.
J Med Chem (2004) 47 : 5235 -5243
PubMed 15456267 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.73 5.73

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL46942 1 5.73

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL46942 IC50 = 1866.0 nM 5.73