Assay Detail
Binding
CHEMBL830870
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In vitro inhibitory concentration against heart and muscle fatty acid binding protein(H-FABP)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Tissue | Muscle tissue |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.04 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL82293 | PALMITIC ACID | -1.0 | 1 | 5.58 |
| CHEMBL184817 | — | — | 1 | 5.24 |
| CHEMBL427320 | — | — | 1 | 5.01 |
| CHEMBL363032 | — | — | 1 | 5.00 |
| CHEMBL364141 | — | — | 1 | 4.38 |
| CHEMBL185595 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL82293 | PALMITIC ACID | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL184817 | — | IC50 | = | 5700.0 | nM | 5.24 |
| CHEMBL427320 | — | IC50 | = | 9800.0 | nM | 5.01 |
| CHEMBL363032 | — | IC50 | = | 9900.0 | nM | 5.00 |
| CHEMBL364141 | — | IC50 | = | 42000.0 | nM | 4.38 |
| CHEMBL185595 | — | IC50 | < | 600.0 | nM | - |