Assay Detail
Binding
CHEMBL830954
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Inhibition of Alpha-2 adrenergic receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Indolebutylamines as selective 5-HT(1A) agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.73 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL363537 | — | — | 1 | 6.05 |
| CHEMBL8412 | IPSAPIRONE | 2.0 | 1 | 6.00 |
| CHEMBL360419 | — | — | 1 | 5.70 |
| CHEMBL187196 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL363537 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL8412 | IPSAPIRONE | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL360419 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL187196 | — | IC50 | = | 7000.0 | nM | 5.16 |