Assay Detail
Binding
CHEMBL831065
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against Aurora kinase A
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Potent and selective Aurora inhibitors identified by the expansion of a novel scaffold for protein kinase inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.57 | 7.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL363160 | PHA-680632 | — | 1 | 7.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL363160 | PHA-680632 | IC50 | = | 27.0 | nM | 7.57 |