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Assay Detail

CHEMBL831584

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Glycogen synthase kinase-3 beta
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis and identification of [1,3,5]triazine-pyridine biheteroaryl as a novel series of potent cyclin-dependent kinase inhibitors.
Kuo GH, Deangelis A, Emanuel S, Wang A, Zhang Y, Connolly PJ, Chen X, Gruninger RH, Rugg C, Fuentes-Pesquera A, Middleton SA, Jolliffe L, Murray WV.
J Med Chem (2005) 48 : 4535 -4546
PubMed 15999992 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.70 7.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL191336 1 7.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL191336 IC50 = 20.0 nM 7.70