Assay Detail
Binding
CHEMBL831672
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration tested against Cyclin dependant kinase 4-cyclinD1
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
Cyclin-dependent kinase 4/cyclin D1 (CHEMBL1907601) ↗| Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
Publication
Novel CDK inhibition profiles of structurally varied 1-aza-9-oxafluorenes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.54 | 4.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL361573 | — | — | 1 | 4.54 |
| CHEMBL179219 | — | — | 1 | - |
| CHEMBL183408 | — | — | 1 | - |
| CHEMBL361537 | — | — | 1 | - |
| CHEMBL361565 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL361573 | — | IC50 | = | 28700.0 | nM | 4.54 |
| CHEMBL179219 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL183408 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL361537 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL361565 | — | IC50 | > | 100000.0 | nM | - |