Assay Detail
Functional
CHEMBL832357
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Inhibitory concentration against HT-29 cell line
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Conformationally restricted analogues of psorospermin: design, synthesis, and bioactivity of natural-product-related bisfuranoxanthones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.26 | 6.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL369474 | PSOROSPERMIN | — | 1 | 6.19 |
| CHEMBL189987 | — | — | 1 | 5.15 |
| CHEMBL192424 | — | — | 1 | 4.44 |
| CHEMBL363845 | — | — | 1 | - |
| CHEMBL446440 | — | — | 1 | - |
| CHEMBL372898 | — | — | 1 | - |
| CHEMBL365964 | — | — | 1 | - |
| CHEMBL192962 | — | — | 1 | - |
| CHEMBL365115 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL369474 | PSOROSPERMIN | IC50 | = | 640.0 | nM | 6.19 |
| CHEMBL189987 | — | IC50 | = | 7130.0 | nM | 5.15 |
| CHEMBL192424 | — | IC50 | = | 36670.0 | nM | 4.44 |
| CHEMBL363845 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL446440 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL372898 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL365964 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL192962 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL365115 | — | IC50 | > | 30000.0 | nM | - |