Assay Detail
Functional
CHEMBL832363
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human cancer SKOV-3 cell line
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-OV-3 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Synthesis and biological evaluation of chalcones and their derived pyrazoles as potential cytotoxic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.68 | 5.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL190474 | — | — | 1 | 5.21 |
| CHEMBL195642 | — | — | 1 | 5.08 |
| CHEMBL32353 | — | — | 1 | 4.68 |
| CHEMBL187451 | — | — | 1 | 4.46 |
| CHEMBL187681 | — | — | 1 | 4.41 |
| CHEMBL61592 | — | — | 1 | 4.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL190474 | — | IC50 | = | 6090.0 | nM | 5.21 |
| CHEMBL195642 | — | IC50 | = | 8350.0 | nM | 5.08 |
| CHEMBL32353 | — | IC50 | = | 21010.0 | nM | 4.68 |
| CHEMBL187451 | — | IC50 | = | 35080.0 | nM | 4.46 |
| CHEMBL187681 | — | IC50 | = | 39060.0 | nM | 4.41 |
| CHEMBL61592 | — | IC50 | = | 56510.0 | nM | 4.25 |