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Assay Detail

CHEMBL832528

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Functional
Inhibitory activity against L1210 cell growth for 48 hr
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L1210
Confidence 1 — Organism
Curated By Intermediate

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

Synthesis and biological evaluation of aminopolyamines.
Bergeron RJ, Huang G, McManis JS, Yao H, Nguyen JN.
J Med Chem (2005) 48 : 3099 -3102
PubMed 15857111 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.81 5.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL364961 1 5.10
CHEMBL18794 BIS(ETHYL)SPERMINE 1 4.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL364961 IC50 = 8000.0 nM 5.10
CHEMBL18794 BIS(ETHYL)SPERMINE IC50 = 30000.0 nM 4.52