Assay Detail
Binding
CHEMBL832688
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of PRP-1 peptide from human Nck kinase SH3 domain by fluorescence polarization
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Identification and specificity studies of small-molecule ligands for SH3 protein domains.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 4.05 | 4.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL361660 | — | — | 1 | 4.05 |
| CHEMBL61236 | — | — | 1 | - |
| CHEMBL366327 | — | — | 1 | - |
| CHEMBL426622 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL361660 | — | EC50 | = | 90000.0 | nM | 4.05 |
| CHEMBL61236 | — | EC50 | = | 150000.0 | nM | - |
| CHEMBL366327 | — | EC50 | = | 300000.0 | nM | - |
| CHEMBL426622 | — | EC50 | > | 500000.0 | nM | - |