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Assay Detail

CHEMBL832777

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of cyclin-dependent kinase 5/p25
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 6 — Multiple protein complex / RNA
Curated By Autocuration

Target

Cyclin-dependent kinase 5/CDK5 activator 1 (CHEMBL1907600)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Mechanism of CDK5/p25 binding by CDK inhibitors.
Mapelli M, Massimiliano L, Crovace C, Seeliger MA, Tsai LH, Meijer L, Musacchio A.
J Med Chem (2005) 48 : 671 -679
PubMed 15689152 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.00 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL126077 INDIRUBIN-3-MONOXIME 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL126077 INDIRUBIN-3-MONOXIME IC50 = 100.0 nM 7.00