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Assay Detail

CHEMBL832781

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration against integrase-catalysed strand transfer
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Confidence 9 — Direct single protein target
Curated By Expert

Target

Human immunodeficiency virus type 1 integrase (CHEMBL3471)
Type SINGLE PROTEIN
Organism Human immunodeficiency virus 1

Publication

New approaches toward anti-HIV chemotherapy.
De Clercq E.
J Med Chem (2005) 48 : 1297 -1313
PubMed 15743172 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL32865 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL32865 IC50 = 10.0 nM 8.00