Assay Detail
Binding
CHEMBL832892
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In vitro Inhibitory concentration against phospholipase A2 activity of synovial fluid
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis of benzoyl phenyl benzoates as effective inhibitors for phospholipase A2 and hyaluronidase enzymes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.73 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL169 | URSOLIC ACID | 2.0 | 1 | 5.60 |
| CHEMBL188295 | — | — | 1 | 5.60 |
| CHEMBL365712 | — | — | 1 | 4.50 |
| CHEMBL186940 | — | — | 1 | 4.34 |
| CHEMBL425541 | — | — | 1 | 4.25 |
| CHEMBL189359 | — | — | 1 | 4.07 |
| CHEMBL187531 | — | — | 1 | - |
| CHEMBL187905 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL169 | URSOLIC ACID | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL188295 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL365712 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL186940 | — | IC50 | = | 46000.0 | nM | 4.34 |
| CHEMBL425541 | — | IC50 | = | 56000.0 | nM | 4.25 |
| CHEMBL189359 | — | IC50 | = | 86000.0 | nM | 4.07 |
| CHEMBL187531 | — | IC50 | = | 156000.0 | nM | - |
| CHEMBL187905 | — | IC50 | = | 123000.0 | nM | - |