Assay Detail

CHEMBL832964

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Inhibitory concentration againstHuman Karpas 299 Anaplastic Large Cell Lymphoma (CD30+) at 96th hour; n=9

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Design, synthesis, and in vitro evaluation of dipeptide-based antibody minor groove binder conjugates.

Jeffrey SC, Torgov MY, Andreyka JB, Boddington L, Cerveny CG, Denny WA, Gordon KA, Gustin D, Haugen J, Kline T, Nguyen MT, Senter PD.
J Med Chem (2005) 48 : 1344 -1358
PubMed 15743178 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.93	8.93

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL117142	—	—	1	8.93

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL117142	—	IC50	=	1.17	nM	8.93